High-Alert Medications: Safeguarding against Errors: Introduction 

Although most medications have a wide margin of safety, a few drugs have a high risk of causing patient injury or death if they are misused. Special precautions are needed to reduce the risk of error with these "high-alert" medications. Errors with these drugs may not be more common than with other medications, but their consequences can be more devastating.
High-alert medications can be targeted for specific error-